MS+Materials+and+Methods

Materials and Methods

Research was done using PubMed to find articles that related to Multiple Sclerosis. Primary researched articles were identified, and secondary sources were reviewed for context. The IL23A gene was identified as a gene of interest. A previous study sequenced the IL23A gene for 206 Chinese Han patients with inflammatory demyelinating diseases (IDD) and assessed SNPs within or close to those genes (Li et al., 2016). The study also analyzed the serum levels of IL23A in IDD patients using ELISA. The study performed a statistical analysis using Chi-Square Tests as implemented in SPSS (version 19.0). They used online software OEGE to carry out a Hardy-Weinberg equilibrium test of the population. Ensembl was used to research more about population genetics of the rs2371494 SNP. The two Geneworld maps, the genetic risk world map, and thegenetic risk human relationship map, were used to research more about the genetic risk of Multiple Sclerosis in the United States compared to the rest of the world.

__Tools used: __

Esembl

Search term: rs2371494

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Geneworld map

Search term: Multiple Sclerosis

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