BroaderImpactSCD

Broader Impact

Other Medical Complications: Blood runs throughout the entire body, so it is only natural for sickle cell to cause the affect individual to have several different problems all over. The disease can cause neurological problems that would not normally be found with ordinary testing. Neurological impairment, only observed through behavior, is one of these types of complications. Acute silent cerebral infarction can be detected through a specific type of MRI but the condition can be fatal. Sickled cells are not shaped correctly for the proper movement through vessels which causes them to often times form blockage and buildup. A cerebral infarction is one of those types of buildups and results in a stroke. Gastrointestinal issues that can lead to organ damage are also attributed the SCD. The gallbladder may be damaged due to the buildup of hemoglobin stones, biliary sludge and obstruction. The liver is affected by issues like reoccurring ischemia which can lead to its enlargement. The patient can even be more susceptible to infections which could become fatal.

Current Treatment: As mentioned on the discussion page, Hydroxyurea has been found to be the most effective medication for treating patients diagnosed with sickle cell. Other options such as blood transfusions and organ transplants are also use but only in severe cases due to the possibility of a complication occuring. In some cased, strong opiods may have to be used to treat the patient's severe pain.

Future Treatment: Gene therapy is thought to be the possible answer to many genetic diseases. Actual trials and case studies have yet to be found to prove that this is currently a way to cure the disease. The theory is to alter the DNA of the patient so eliminate the mutation of the HBB gene so that

Precautions and Education for All It is being found that adolescents diagnosed with SCD are found to have problems transitioning from children to adults. Due to the several conditions that occur from the damage sickle cell enacts on the body, patients tend to miss a large amount of school. They then tend to be behind academically. Their ailments also make it hard to live normal daily lives and do daily chores. In order to assist these patients, programs are being implemented either in schools or through the help of occupational therapists to teach the patients how to manage their health by managing their medications and medical appointments. They are also assisting the patients to manage their money, obtain vocational skills and encouraging them to self-advocate.

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