CNL;+Discussion

The sequence alignments of each gene showed more similarity in proteins than in nucleotides. The phylogenetic trees assembled from these alignments showed similarity across genes as well; Tamura-Nei values were generally strong and were generally repetitive (meaning that genes were conserved among similar species). These trends were relatively consistent among the genes investigated. Protein trees did vary from their respective gene trees, with lower Tamura-Nei values on average and some species similarities either diverging or converging with others. From protein analysis, it appears that the proteins transcribed from these genes do not interact with each other, as shown in the protein interaction maps.
 * Data Analysis; **

All four genes investigated play some role in the progression of CNL. The //CSF3R// T618I mutation is most common in diagnosed patients, but mutations in the //ASXL1, CALR// and //SETBP1// genes were also present in some cases, and contribute to the progression of CNL. The protein sequences of these genes are well preserved across species, while the nucleotide sequences are not. Most deviations are missense mutations, but still produce a similar protein.
 * Conclusions; **

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