Personal+Genomics+Behind+Endometriosis+Abstract

=__Abstract __=

Endometriosis is becoming one of the most common reproductive diseases for women in their young adult life worldwide. Research has suggested that many of the causes for the rise in rates of endometriosis are directly related to the environment. However, there is also evidence that shows personal genomics does have an influence on the disease risk for endometriosis. Personal genomics cannot cause an individual to develop endometriosis, but certain combinations of alleles for specific SNP variants can increase the disease risk of endometriosis for women. The purpose of this research study is to explore what genes of interest are involved in the personal genomics of endometriosis. The methods of research conducted for this disease risk study were completed by using online resources such as the GWAS catalog, HapMap, 1000 genomes database, and Ensembl. In addition to online database resources, primary articles of research were also used to gain more evidence on the genes affecting the disease risk of endometriosis. Currently there are over 60 different genes being tested for their relation to endometriosis, unfortunately there is still no proven theories regarding which genes have most impact on the disease risk of endometriosis. For this personal genomics study, the goal is to determine more information on the impacts of the WNT4, CHD5, CDKN2BAS1, and ESR1 gene on the disease risk of endometriosis.

=Genes of Interest = =Home =