Clotting+Thrombin

=Venous Thromboembolism - A Study in Personal Genomics= Jacqueline Tims Fall 2011 Genomics and Bioinformatics

In deciding to select a Genomics and Bioinformatics project, I was motivated by a lecture I attended at Dartmouth Medical School in March this year. Dr. Jason Moore was introducing the concept of personal genomics to a class of fourth year medical students and the new online availability of genetic information through a company called 23andMe. This company offers the opportunity to sequence the Single Nucleotide Polymorphism’s (SNP’s) in your own genome for a modest $99. Over the summer, my aunt, a retired anesthesiologist, also called to say she had used the service and was very impressed. This proved to be a heady incentive: - I was intensely curious as to my own sequence data and what differences there maybe to my maternal aunt. I also enlisted the help or my good friend Nancy as a control ( of sorts!)
 * Introduction**

23andMe ....... The Disease ....... The Gene ....... The Protein ........Clotting Pathways.... The SNP ....... Sequence Homology ... References....