Personal+Genomics+of+Alzheimer's+Disease+Works+Cited

 I wish to thank Dr. Sarah Prescott for her advice and guidance in this research project. I would also like to thank Nancy F. and Dr. Sarah Prescott for use of their 23andMe data.
 * Acknowledgements **

Bennett, David A. MD, Yu, Lei PhD et al. (2015) Epigenomics of Alzheimer’s Disease. Transl Res., 165(1), 200-220. doi: 10.1016/j.trsl.2014.05.006.
 *  Literature Cited **

Chen, C.J., Chen, C.C. et al. (2013). Effects of the Apolipoprotein E ε4 Allele on Functional MRI during n-Back Working Memory Tasks in Healthy Middle-Aged Adults. AJNR Am J Neuroradiol, 34, 1197-1202. []

Coon, Keith D. Ph.D., Myers, Amanda J. Ph.D., Craig, David W. Ph.D. et al. (2007). A High-Density Whole-Genome Association Study Reveals that APOE Is the Major Susceptibility Gene for Sporadic Late- Onset Alzheimer’s Disease. J Clin Psychiatry, 68(4), 613-618.

Green, Robert M.D., M.P.H., Roberts, J. Scott Ph.D., et al. (2009). Disclosure of APOE Genotype for Risk of Alzheimer’s Disease. N Engl J Med, 361(3), 245-254. doi:10.1056/NEJMoa0809578.

Health and Traits- Alzheimer’s Disease, Technical Report. Accessed 03/2016. Retrieved from []

Linnenbringer, Erin, MS, Roberts, J. Scott, et al. (2010). “I Know What You Told Me, But This is What I Think:” Perceived Risk of Alzheimer Disease Among Individuals Who Accurately Recall Their Genetics-Based Risk Estimate. Genet Med, 12(4), 219-227. doi:10.1097/GIM.0b013e3181cef9e1.

Locations of features associated with ALZHEIMER DISEASE 2, DUE TO APOE4 ISOFORM. Accessed 3/2016. Retrieved from http://useast.ensembl.org/Homo_sapiens/Phenotype/Locations?db=core;g=ENSG00000130203;ph=25274;r=19:44905812-44909025;t=ENST00000434152

NMR Structure of full length apoE3, RCSB PDB. Accessed 3/2016. Retrieved from []

Reitz, Christiane (2015). Genetic Diagnosis and Prognosis of Alzheimer’s Disease: Challenges and Opportunities. Expert Rev Mol Diagn, 15(3), 339-348. doi:10.1586/14737159.2015.1002469

Salloway, Stephen M.D., Sperling, Reisa M.D., et al. (2014). Two Phase 3 Trials of Bapineuzamab in Mild-to-Moderate Alzheimer’s Disease. N Engl J Med, 370(4) 322-333: doi:10.1056/NEJMoa1304839.

Seo EH, Lee DY, Lee J-M, Park J-S, Sohn BK, et al. (2013). Influence of APOE Genotype on Whole-Brain Functional Networks in Cognitively Normal Elderly. PLoS ONE, 8(12): e83205.doi:10.1371/journal.pone.0083205

Showing 3.611kbp from chr19, positions 44,710,665 to 44,714,275, International HapMap Project. Accessed 3/2016. Retrieved from https://hapmap.ncbi.nlm.nih.gov/cgi-perl/gbrowse/hapmap28_B36/#search

Douglas, Pat. 27 May, 2015. "Still Alice" Offers Insite to Alzheimer's Disease. //Great Falls Tribune.// Accessed April 2016. Retrieved from http://www.greatfallstribune.com/story/entertainment/2015/05/27/still-alice-offers-insight-alzheimers-impacts/28018825/.

Top Interacting Chemicals- APOE. Comparative Toxicogenomics Database. Accessed 4/2016. Retrieved from http://ctdbase.org/detail.go?type=gene&acc-348

Wolf, Andrew B., & Valla, Jon et al (2013). Apolipoprotein E as a β-amyloid-independent Factor in Alzheimer’s Disease. Alzheimer’s Research & Therapy, 5:38. Retrieved from []

Zettler, Patricia J. JD, Sherkow, Jacob S. JD, and Greely, Henry T. JD. (2014) 23andMe, the Food and Drug Administration and the Future of Genetic Testing. JAMA Internal Medicine, 174(4), 493-494.

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