Alzheimer's Disease

Audrey Ameen
Email: alj425@wildcats.unh.edu

Introduction

Alzheimer’s disease (AD) is a disorder that results in the gradual degeneration of nerves causing memory loss. There are two different types of Alzheimer’s disease sporadic AD (SAD) and familial AD (FAD). Both types result from gene mutations, but different genes cause each type. SAD is caused by the mutation in the apolipoprotein E (ApoE) and FAD is a result of mutations to the amyloid precursor protein (APP), presenilin 1 (PS1), and presenilin 2 (PS2). Symptoms of SAD start becoming noticeable around the age of 5, while the symptoms of FAD become noticeable during an individual’s 40s and 50s. Most people associate forgetfulness with Alzheimer’s, but there are other symptoms that depend on the individual who is diagnosed based on their personality, life experiences, and current circumstances.



Research Questions

1. If other species have the ApoE gene, can they also get Alzheimer’s disease, or is it a disease specific to humans?

2. How do these drugs help with treating Alzheimer’s disease?

NEXT: What Are the Causes of Alzheimer's Disease?
What Are the Effects of Alzheimer's Disease?
Treatments for Alzheimer's Disease
Methods Used
Data and Results
Data Analysis
Work Cited

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